SmartFlow Technologies, Inc.
Proven Performance in High-Solids,
High-Temperature Filtration
Our proprietary High Solids TFF (HSTFF™) platform has been helping customers solve the most demanding separation challenges where high solids, sticky feeds, and elevated temperatures make traditional filtration challenging.
A Glimpse Into SmartFlow’s
Operations in Sanford, NC
Benefits of Working With SmartFlow
SmartFlow partners with customers from concept to commercialization, providing a guided approach to scale with technologies that extend the capabilities of traditional filtration methods.
- High Solids TFF (HSTFF™)-high-solids, high temperature operation capabilities
- 6 stage process to de-risk scale up
- Ongoing post-launch maintenance support program
- Patented membrane-based platform for multiple applications
Benefits of the SmartFlow Design Platform
SmartFlow’s open channel High Solids TFF (HSTFF™) membrane-based platform
- Concentrates challenging streams to high solids
- Improves recovery and dryer efficiency
- Enables targeted separations
- Integrates features like DiaSync® diafiltration with product recovery and concentration
Built for Demanding Processing Environments
SmartFlow systems operate reliably under high heat and viscosity while maintaining consistent performance from lab to plant scale.
- Operates reliably at temperatures up to 85°C (peak of 90°C)
- Produces viscosities of >500,000 cP
- Scales seamlessly from lab to commercial size, utilizing SmartFlow’s modular design
Thin Stillage Concentration
High Solids, Higher Efficiency
The system reaches solids levels beyond conventional membranes, improving drying performance and overall process efficiency.
- Concentrates streams to >95% total solids on a wet weight basis (and has exceeded 99% in some cases)
- Achieves dry weight concentrations exceeding 55% in biological applications, supporting higher downstream efficiency
- Increases spray dryer throughput typically by 15–25% by delivering higher concentration feeds
High Solids Concentration
Integrated Concentration, Diafiltration & Water Reuse
DiaSync® unifies concentration and diafiltration while reusing permeate intelligently. Instead of discrete batch steps with fresh water additions, DiaSync® recycles the appropriate permeate fraction, cutting external water demand and shortening time‑to‑target (conductivity, buffer exchange, salt removal, etc.).
- Integrated concentration and diafiltration in one control recipe
- Permeate reuse strategies that reduce freshwater draw and wastewater volume
DiaSync® Process
Energy Savings and Product Value Recovery
Higher concentrated product streams reduce energy use and enable selective recovery of valuable components.
- Cuts energy consumption compared to evaporative concentration alone
- Enables targeted membrane separations of proteins, sugars, and other valuable fractions
Mushroom Processing
(Enzyme Recovery)
See It In Action
If You Can Pump It,
We Can Filter It
This feasibility test video demonstrates fermented algae concentrated with the HSTFF™ process to the point where it was no longer pumpable.
Areas of Expertise
Industries We Serve
At SmartFlow Technologies, we deliver tailored separation solutions across industries such as Renewable Fuels, Dairy, Precision Fermentation, Nutraceuticals, Biopharmaceutical, Food & Bev, Specialty Separations, Process Water, Chemical Processing, FOG, and more. For each application, we configure membranes, channel geometry, and operating windows to the specific feed and objectives, helping customers increase yield, stabilize quality, reduce operating costs, and improve sustainability.
Corn Ethanol Stillage
Biopharmaceutical
Precision Fermentation
Nutraceutical
Dairy
Food & Bev
Specialty Separations
Process Water
Chemical Processing
FOG Separation
Starch Recovery
Digestate
Customer Journey
SmartFlow’s Approach:
The 6-Stage Project Development Program
A structured, low-risk path from goals to full-scale deployment.
The program begins by identifying the goals, defining objectives, and prioritizing opportunities. Feasibility is then verified on actual materials through proof-of-concept testing. From there, SmartFlow develops and optimizes process conditions, membranes, and economics before confirming performance at pilot scale on a right-sized system, supported by SmartFlow’s large rental fleet. The pilot data is used to engineer the plant-scale system(s) with appropriate automation, documentation, and commissioning. Finally, the program standardizes performance across multiple facilities and sustains uptime through ongoing support.
Learn more about the six stages below.
Ongoing Support
Preventive Maintenance and Service Program
Proactive Service. Predictable Results.
SmartFlow’s Preventive Maintenance and Service Program ensures systems operate to spec through scheduled service visits, module rotation, and oversight. The program reduces demand on plant personnel while supporting steady, high-yield performance.
- Reliable Output – Stable, repeatable system performance
- Longer Asset Life – Maintenance that protects key components
- Budget Control – Locked-in service pricing for cost clarity
- Hands-Off Upkeep – SmartFlow engineers manage inspections and service
- Responsible Recovery – Spent modules recycled or handled sustainably
Trusted Experience
We proudly serve corn ethanol stillage, dairy, precision fermentation, nutraceutical, biopharmaceutical, food & beverage, specialty separations, process water, chemical processing, FOG separation, starch recovery, and digestate. With 100+ patents issued and global installs, our systems increase yield and throughput, cut OPEX, and support sustainability. They run 24/7 in high-solids duty at 85°C target with 90°C peak, with performance maintained during planned windows. We build to URS, provide FAT/SAT, commissioning, training, and support documentation requirements. Post-startup, our Preventive Maintenance and Service Program ensures peak performance with preventive service, performance reviews, and module management.